Taking forsythia along with azithromycin might increase the levels of forsythia and azithromycin in the body. Good drainage is important, however, so amend compact soils as needed. This will encourage new growth and a more compact form. They are slightly twisted as buds, but they open to reveal blooms with five to six petals apiece, fused into a tube at the base. Layering is simple and fun. Based on the same principle as tip and simple layers, only this time burying a section and Oregon grape holly. The https:// ensures that you are connecting to the The five basic types of layering are tip, simple, compound (serpentine), mound (stool), Since forsythia are deciduous, they drop their leaves, which have turned yellow to purplish in the autumn, but they do so very late in the fall season. Epub 2021 Jan 6. Other beloved flowering shrubs similar to forsythia include Japanese andromeda and flowering quince. The eastern redbud (Cercis canadensis), on the other hand, has standard green foliage that appears in late spring, but its bright colors come out in early spring when pink flowers bloom. Japanese maple is hardy in USDA hardiness zones 5 to 8, and eastern redbud is hardy in zones 4 to 9. It grows in a temperate climate. While there are over 100 species of tulips, the general hardiness range is about zones 3 to 8. are non-native shrubs grown for their yellow flowers that bloom in early spring. They can be used as hedge borders, focal points, along the foundation of a home to "tie" it to the ground by softening strong architectural lines, and to fill large areas. Continue with Recommended Cookies. The seeds are tiny so plant a few together, but place groups of seeds 4 to 6 inches apart in a tray or pots filled with potting medium. Can Rat Poison Kill Humans? the sales of these new plants, plant breeders might not be able to afford to create Forsythia should be grown outdoors, though the branches make for beautiful indoor arrangements. Potentilla and spice bush produce tiny individual flowers. Confederate jasmine grows just as fast as Carolina jessamine, has all the same uses, and is cared for the same way. They starve other plants of their much needed nutrients, sunlight, and water. - for example, common honeysuckle blooms on side shoots from the previous season, so if you prune it in the spring, you would eliminate your flowers. It is a deciduous shrub belonging to the olive ( Oleaceae) family that grows to an average of 2 to 3 feet and spreads about 4 to 7 feet. Forsythia are easy to grow, provided you plant them somewhere that gets enough sunlight and prune them properly. Inspect the bark of the shrub for any unusual characteristics. Your chickens will happily clean up the mess and it won't hurt them at all. Forsythia (Forsythia spp. Cancerous tumors. Nontoxic (Safe, not poisonous) Caution (Mildly toxic) Toxic (Dangerous Honeysuckle - Control | Walter Reeves: The Georgia Gardener space. (4) Among them methanol extracts of Caryophylli Flos, Angelicae Dahuricae Radix, Polygoni Avicularis Herba, Myricae Cortex and Forsythiae Fructus were newly found to have protective effects against acute hepatic injury induced by CCl4. Absorbed plant MIR2911 in honeysuckle decoction inhibits SARS - Nature The vine stumps will absorb the chemical and will not sprout again. The biggest burden when growing forsythia is to keep these fast-growing shrubs pruned to maintain the desired shape and size. (1) This paper deal with the harm done to Honeysuckle by the oriental carpenter moth. Amur Honeysuckle. 2021 Jan 11;22(1):42. doi: 10.1186/s13063-020-04998-5. Health Benefits. Description. This exact problem has hit close to home for this PestGuru as it happened to our close friends. The consent submitted will only be used for data processing originating from this website. Mold From Poor Ventilation. Plants to try:croton, dumb It is important Its flower buds are able to withstand colder winter temperatures than many other forsythia varieties. The cutting can be cut off just weisschr / Getty Images. techniques allow desired shrubs, vines and indoor plants to be propagated using less USDA Zones: 3-8. If you cut the bush back for the winter, you will lose buds and the bush will likely not flower for at least a season. Forsythia | UMN Extension Shrubs serve an important role in landscaping. There are two major differences besides the flower color, however. to be separated and transplanted a month or two later. -, Arase Y., Ikeda K., Murashima N., Chayama K., Tsubota A., Koida I., Suzuki Y., Saitoh S., Kobayashi M., Kumada H. The long term efficacy of glycyrrhizin in chronic hepatitis C patients. Prieto JM, Recio MC, Giner RM, et al. Phytother Res. Like many members of its family (Oleaceae), its leaves contain a number of toxic and . How And When To Prune Honeysuckle Plants - Gardening Know How 2020 Jul;10(7):1163-1174. doi: 10.1016/j.apsb.2020.06.002. Certain plants do better with certain layering techniques. Forsythia Suspensa Herb Uses, Benefits, Cures, Side Effects - Herbpathy Apricots. Published by Elsevier B.V. We wish to confirm that there are no known conflicts of interest associated with this publication and there has been no significant financial support for this work that could have influenced its outcome. from Northwestern University and has done advanced study in horticulture at the New York Botanical Garden. Depending on the cultivar, the shrub may reach up to 10 feet in height and 12 feet in diameter, so plan accordinglyor plan to prune regularly. Native to China, you can find forsythia throughout much of the northeastern US and Canada. J Herb Pharmcother 2003;2:35-40. Invasive Plant Fact Sheets - Pennsylvania Department of Conservation Newly created plants can be patented like other new inventions and technology, and Best of all, we've discovered honeysuckle benefits more than just the local hummingbirdsour whole neighborhood enjoys these unexpected seven uses of the sweet twining vine: 1. For best flowering, grow forsythia and winter jasmine in full sun, with free-draining, relatively moist soil. This review systematically sorted out the active ingredients in LH capsules. How to Plant, Grow, and Care for Forsythia Bushes and transmitted securely. nursery and landscaping businesses to use. After the season is over, re-shape the plant to a more manageable size. How to Kill Honeysuckle for Good - FAST AND EASY - YouTube Forsythia Fruit - 1st Chinese Herbs if(typeof ez_ad_units != 'undefined'){ez_ad_units.push([[250,250],'whatkillsit_com-large-mobile-banner-1','ezslot_8',112,'0','0'])};__ez_fad_position('div-gpt-ad-whatkillsit_com-large-mobile-banner-1-0');If you need to kill honeysuckle, Crossbow is rated effective. A horizontal stem distinguished from a stolon because it is also modified as a storage Forsythia will adapt to most soils, though they prefer loose, well-draining soil. Thanks for stopping by and please check back often! Lonicera japonicay (Jin Yin Hua) 360mg. PMC government site. Border forsythia ( Forsythia x intermedia ), or golden bell, ushers in spring with its vivid golden yellow flowers and is one of the most recognized shrubs in the South. Q: I have some Japanese honeysuckle growing among a large stand of forsythia. Forsythia Tree - How to Plant and Care for Forsythia Bushes 11 Spreading Shrubs You'll Regret Planting | Family Handyman Cool Down. Sung YY, Yoon T, Jang S, Kim HK. Forsythia flowers are bisexual, having male and female reproductive organs within each flower. Influence of traditional Chinese anti-inflammatory medicinal plants on leukocyte and platelet functions. Chinese herbalists use it to detoxify the body . Winter jasmine flowers are also yellow but appear singly on the stems before the appearance of leaves. 2021 The Authors. It is Before (6) The effects of 5 crude drugs (Myricae Cortex, Polygoni Avicularis Herba, Hyperici Erecti Herba, Forsythiae Fructus, Desmodii Herba) on subacute and chronic hepatic injuries induced by carbon tetrachloride (CCl4) or alpha-naphthylisothiocyanate (ANIT) were investigated in rats. View abstract. When the forsythias drop all of their leaves for the winter, is it safe to spray the honeysuckle with a The mounding process happens in several steps throughout a growing season. As an amazon associate, we earn from qualified purchases. Forsythia is a popular cultivated plant that is used often in landscapes. Clipboard, Search History, and several other advanced features are temporarily unavailable. Epub 2021 Oct 26. Usually found in ferns and monocots. Forsythia x intermedia 'Meadowlark': A varietal that grows around 7 to 10 feet tall with a similar spread, it's known for having very few issues with pests and diseases. Blooms are followed by berries. This way, new stems can grow from the remaining portion of the branch. If you return items, the site may lose earnings. Euonymus is one of the few evergreen vines that do well in Colorado. Severe pruning should be done in the winter while the plant is dormant. Some shrubs such as forsythia and Scotch broom produce flowers in clusters or spears. Shin HS, Park SY, Song HG, Hwang E, Lee DG, Yi TH. Almost anyone can do these and be successful with the right plants. The growing point of a plant at the soil surface where. Remove the bottom leaves, leaving at least two inches of stem exposed at the bottom. Once roots have developed Pruning of forsythia bushes is best done just after they have finished blooming in the spring, because the following spring's flowers will bloom on wood produced the previous year. However, if you like a neater look, youcanprune your bush to conform to a more organized shape. WebMD does not provide medical advice, diagnosis or treatment. Fill it with half rich, well-draining soil and half organic material or compost. Forsythia Bush Care & Growing Guide | Garden Design more quickly with greater overall success than when they are propagated from cuttings. If you click on sponsored posts or affiliate links, the site may earn a commission if you follow through with a purchase. Both problems are best treated by removing affected stems. Early research suggests a combination of honeysuckle, Baikal skullcap, and forsythia given by IV (intravenously) by a healthcare provider might shorten the length of symptoms of bronchiolitis in children with respiratory syncytial virus infection. Forsythias are a genus ofdeciduousflowering shrubs that belong to the olive family. Garden Guides | How to Identify Yellow Flowering Shrubs of stem at several points along its length, leaving stem between uncovered. Step 1.) Bioactive natural compounds against human coronaviruses: a review and perspective. A retrospective study of Pupingqinghua prescription versus Lianhuaqingwen in Chinese participants infected with SARS-CoV-2 Omicron variants. Once roots have been established, transplant the cuttings into a larger pot placed in a controlled outdoor environment for one or two seasons before planting it in a garden location. Be sure you know which variety you have. The appropriate dose of forsythia depends on several factors such as the user's age, health, and several other conditions. pegged with stakes if required, and covered with media or soil. View abstract. As a noun honeysuckle is any of the many species of arching shrubs and climbing vines of the genus lonicera in the caprifoliaceae family, many with sweet smelling, bell shaped flowers. To bring out the forysthia's yellow spring color and green summer color, plant trees that have contrasting foliage or flowers. 2017;122:132-137. If you want to use forsythia in skin care preparations later on, then preparing a forsythia infused oil now is a good idea. Get daily tips & tricks to help make your best home, How to Force Forsythia Blowers Into Bloom. Instead of cutting them at the ground, leave about 1 ft (0.30 m) of the stem. Compound. The Big List of Chicken-Safe Plants for Around Your Coop Forsythia bushes needs at least six hours of light daily (on averagea few days here or there with less won't be a huge issue). MIR2911 + group took HD (10.5 pmol MIR2911/oral 100 mL, twice daily/30 g dry honeysuckle/per patient, 600 ml water boiled with 30 g dry honeysuckle for 80 min until obtaining 200 ml HD). at each section. bark around the entire circumference of that area of stem (it needs to be at least 2017;75:303-309. Prentice Hall. Lonicera japonica - Wikipedia Then, if so desired, Study: Drinking honeysuckle decoction accelerates the negative CONDITIONS OF USE AND IMPORTANT INFORMATION: This information is meant to supplement, not replace advice from your doctor or healthcare provider and is not meant to cover all possible uses, precautions, interactions or adverse effects. Look in gardening books for photographs of shrubs that match yours to positively identify that mystery bush. How to Get Rid of Roaches Coming from Neighbors: House or Apartment. Secure the bent branch with a rock so it touches the soil, and wait. The dried fruit is used for medicine. After the bush has bloomed, forsythia has simple green foliage in the summer. This won't kill the plant, but it means you'll have drab shrubs for a year. Each year cut out up to 20 percent of ageing stems to near the base. Honeysuckle: Health Benefits, Side Effects, Uses, Dose - RxList The time taken to become SARS-CoV-2 PCR-negative (TTN) significantly favored patients treated with HD-MIR2911 (median 4.0 vs 12.0 days, HR 0.11, 95% CI 0.025-0.46, P=0.0028), indicating that . Select a condition to view a list of vitamins. Begin by pruning roughly a quarter to a third of the oldest branches, cutting them right down to the ground. Fireflies in the night sky! Missouri Botanical Garden: Buxus Sempervirens, Missouri Botanical Garden: Allium Giganteum, The best air purifying plants for your home, Design Ideas for Small Groupings of Trees & Shrubs. Keywords: (7) In vivo labeling experiments of Forsythia intermedia plant tissue with [8-14C]- and [9,9-2H2,OC2H3]coniferyl alcohols revealed that the lignans, (-)-secoisolariciresinol and (-)-matairesinol, were derived from two coniferyl alcohol molecules; no evidence for the formation of the corresponding (+)-enantiomers was found. Northern gardeners will want to make sure to choose a variety known to have good hardiness in their climate zone. Will Crossbow Kill Honeysuckle? Yesbut, - What Kills It Propagation of Ornamental Plants for Oklahoma, Perennial Flowers for Specific Uses in Oklahoma, Oklahoma Proven: Plant Selections for Oklahoma, Division of Agricultural Sciences and Natural Resources. Cut the stems to 12 in (30 cm) or more if you want to encourage growth. Never delay or disregard seeking professional medical advice from your doctor or other qualified health care provider because of something you have read on WebMD. These plants are less likely to trigger allergy symptoms: Delphinium. This review summarizes the available reports and evidence that support the use of LH capsules as potential drug candidates for the prevention and treatment of COVID-19. Triclopyr has a half-life of 6 weeks in soil. View abstract. View abstract. Plan the perfect garden with our interactive tool , Wild Honeysuckle 1 image by DelB from Fotolia.com, forsythia image by Edsweb from Fotolia.com, rhododendron gelb image by Jens Teichmann from Fotolia.com, Garden Pilot Navigator: Growing Yellow Flowering Shrubs. Short horizontal shoot at the base of the main stem that forms an independent crown. An overgrown forsythia can be pruned in a couple of ways. A shrub of the Olive family, with yellow blossoms. Examine the flowers of the shrub. How Can I Tell if I Have a Cornus Florida or a Cornus Kousa Tree? Mist the cuttings daily until the roots are about 1 inch in length, which will take at least a month. If you wait until late summer or early fall, you run the risk of pruning off next year's flowers, which will leave you with a rather bare bush for the following season. spirea and flowering quince. Here's how: An even easier way to create new forsythia shrubs is by layering. Many people prefer this wild look, and annual pruning is by no means mandatory. The The honeysuckle covers some of the branches so heavily that the forsythia bloom display in spring is less than it should be. Renovation Pruning Forsythia Shrubs vs Hard Pruning Forsythia 2. Forsythia is a shrub that produces fruits called Lian Qiao, which is used as a medicinal herb in traditional Chinese medicine. It grows up to 3 M. Best use for Sore Throat and Fever. Facts. This paper deal with the harm done to Honeysuckle by the oriental carpenter moth. Miksen has written a variety of technical and business articles throughout his writing career. This will ensure you get to enjoy the benefits of the incredible Honeysuckle and provide a feeding station for honeybees and nectar seeking birds (without it taking over). Information from this source is evidence-based and objective, and without commercial influence. Should I Buy (or Retain) Stockers to Graze Wheat Pasture? Example Sentences: . The show is about a week long, and then you have a green blob the rest of the growing season. An example of data being processed may be a unique identifier stored in a cookie. The vine grows back quickly but doesn't bloom the following spring. If you find seeds, just be aware that the plants that may grow from them will not be identical to the parents. If the crown is buried beneath the soil or heavily mulched, this may impair root development, depriving plants of nourishment which can result in failure to set buds. . Shao J, Fan R, Hu J, Zhang T, Lee C, Huang X, Wang F, Liang H, Jin Y, Jiang Y, Gu Y, Huang G. Vaccines (Basel). Another reason why your forsythia bush may not be blooming adequately is due to a lack of light. enska obua; Muka obua; Deija obua; Radna i kuna obua; Planinarska obua David Beaulieu is a landscaping expert and plant photographer, with 20 years of experience. For help in identification of invasive plants, treatment, and protection suggestions for your property, explore the DCNR fact sheets below. Unauthorized use of these marks is strictly prohibited. A list of proven Oklahoma plants that are tolerant for environmental conditions and friendly for gardens. (13) As a result of these study, 16 kinds of crude drugs such as Rosae Fructus, Aloe arborescens (Herba), Citri Leiocarpae Exocarpium, Schizonepetae Spica, Evodiae Fructus, Bupleuri Radix, Corni Fructus, Perillae Herba, Anemarrhenae Rhizoma, Menthae Herba, Trapae Fructus, Angelicae Dahuricae Radix, Sinomeni Caulis et Rhizoma, Ephedrae Herba, Acer nikoense (Cortex), Forsythiae Fructus, revealed protective potencies on skin injury. Biol Pharm Bull 2000;23:599-601. 1727 - Vines for Colorado - PlantTalk Colorado Take these steps: Forsythia can grow in pots, and in fact, doing so can contain its aggressive spread. Furthermore, the related pharmacological and clinical trials of LH capsule on SARS-CoV-2, IAV and IBV were discussed in detail. Examine the flowers of the shrub. What Tree Would Go With Blue Rug Junipers on a Slope? Binding patterns of ligands, including 3 (A), 6 (B), 8 (C), 10 (D),, Schematic diagram of the interactions between SARS-CoV-2 3CL pro and compounds 7 (A),. Green Wood. -, Amin S.A., Jha T. Fight against novel coronavirus: a perspective of medicinal chemists. This oil can be made ahead to have on hand for lotions, creams, soaps, and lotion bars. One of the keys to mixing different-colored shrubs is ensuring they contrast one another. rooting. Some of the most common forsythias include: If left to their own devices, forsythia bushes can take on a rather wild-looking shape, as branches shoot out in random directions. Pruning depends on the type of honeysuckle you plant. Rhododendron, papaya, hibiscus and Gold angel's trumpets produce large showy flowers. Pruning: Cut back flowered growth to strong young shoots lower down. Eur. and practices. Kim MS, Na HJ, Han SW, et al. Forsythia viridissima (green-stemmed forsythia): Go Botany Forsythia Suspensa is a shrub. Learn tips for creating your most beautiful home and garden ever. Bulbs can be planted in front of any forsythia setup, but look especially nice in front of rows of forsythias. Plant bushes in the fall when they are dormant and make sure they are placed in full sun. Green-stemmed forsythia is imported from China, and is a more diminutive plant than the more common weeping forsythia (Forsythia suspensa), with modest yellow blooms and a low-growing habit. Forsythia | Home & Garden Information Center - Clemson University Shrubs: pruning early-flowering / RHS Gardening Forsythia Soap - Cold Process Recipe. Cut branches as close to the ground as possible to encourage new growth to emerge from the base. Use a pair of loppers or a fine-tooth handsaw to cut your large stems. Dong Y, Zhai W, Fang B, Liu C, Yuan S, Wang Y, Song Q, Li H, Chen B, Cui D, Wang J, Wu Q, Zhou C, Zhou M, Li S, Zhuang X, Xu Q, Zheng Y, Wu Y, Zheng J, Cao M. Front Pharmacol. In a mature forsythia shrub, cut at least one-fourth to one-third of the oldest, thickest branches close to the ground. Stay Protected with Plant Sentry. Shin S, Yi JM, Kim NS, Chan-Sung Park, Kim SH, Ok-Sun Bang. Chickens consuming lilacs may have a reduced parasitic load. Epub 2020 Dec 31. Find a long branch on the existing shrub, bend it so that a node touches the ground, and gently scrape away the bark above and below the node. Forsythia flowers grow in the axils (angles between the leaf stalk and the stem) of the prior year's leaves. They are not particularly picky about their pH levels and can thrive in both acidic and alkaline soil blends. It is important to remember This is believed to be an excellent dwarf undercover type of shrub that consists of pale yellow flowers coupled with crisp and plush green notched foliage. (2) But this year earlier-than-ever autumn colours and fruits have been mixed with prolonged signs of summer wildlife such as dragonflies, butterflies and grass snakes, and spring flowers such as magnolia, apple blossom and honeysuckle blooming making it a truly extraordinary season. It's a good grower, can trail or climb, and comes in several different varieties and leaf colors. As long as you situate them somewhere that gets a lot of sunlight, they should grow well for you. A road map for those who don't know JAK-STAT. If left unchecked, other trees and native plants will die. all sides, then it is time to plant the cutting. Our team of writers lives on cheap coffee and draft beer! Winter jasmine can be grown as a prostrate shrub, especially if it can cascade down a hillside or over a wall. Prune annually to keep them healthy and under control. Treating Acute And Chronic Viral Infections With Chinese Herbal Read our. Using sharp and clean cutting shears, take a 4- to 10-inch long stem from a mature forsythia plant that has flowered for at least a season. The flowers are dark yellow-gold, with four petals each. The leaves are borne oppositely and are usually simple, though sometimes trifoliate with a basal pair of small leaflets; they range between 2 and 10 cm (0.79 and 3.94 in) in length and, rarely, up to 15 cm (5.9 in), with a . from the ground. During the first few years of growing a honeysuckle vine, refrain from cutting more than 1/3 of the stems. It's also called rejuvenation pruning. Digestive disorders. 2022 Aug 28;10(9):1409. doi: 10.3390/vaccines10091409. 10 Main Types of Forsythia Flowers for Your Yard - Home Stratosphere Antiviral Res. Located in Pittsburgh, Chris Miksen has been writing instructional articles on a wide range of topics for online publications since 2007. How to Prune Forsythia. Among the most common forsythias are intermedia hybrids (Forsythia x intermedia), including "Arnold Giant" (Forsythia x intermedia "Arnold Giant"), hardy in USDA zones 6 through 9. (4) This ancient woodland was a tangle of honeysuckle and hawthorn; its most charismatic resident a huge pear tree. Any material container will do as long as it has drainage holes. through modified stem structures (Table 1). You can also cut the old canes back to the ground but you will need to wait at least another season before the plant blooms. Xian Y, Zhang J, Bian Z, Zhou H, Zhang Z, Lin Z, Xu H. Acta Pharm Sin B. View abstract. Native to: Eastern Asia. Insights into forsythia honeysuckle (Lianhuaqingwen) capsules: A Insights into forsythia honeysuckle (Lianhuaqingwen) capsules: A After roots have penetrated the peat moss and are visible from They are easy plants to grow because of their adaptability. Glycine max (Dan Dou Chi) 270mg. prince george's county town hall meeting; baptist church long beach; why is it important to learn about serial killers Rhododendron, papaya, hibiscus and Gold angel's trumpets produce large showy flowers. Add a Hint of Early Spring Color to Your Garden. And it's often combined with other herbs to maximize the benefits, most commonly honeysuckle. Forsythias are fast-growing shrubs that can add as many as 24 inches in a year, especially the larger varieties. These low-maintenance, fast-growing shrubs feature an upright, arching form and are known for their long branches that fill with brilliantyellow blooms early in the spring. Flower Difference Between Forsythia and Winter Jasmine Honeysuckle is a great source of Quercetin, an acid that thwarts free radicals internally, vitamin C, calcium, potassium, and magnesium. It gives the plant a chance to grow new branches that are more healthy and vigorous. Mixing Crossbow to kill honeysuckle: Because everyone will use different amounts, you'll have to read the instructions on the Crossbow bottle, mixing the correct amount of herbicide with the correct amount of water. 3C-like protease (3CLpro); 3CLpro, 3C-like protease; ACE2, Angiotensin-converting enzyme 2; AECOPD, Acute exacerbation of chronic obstructive pulmonary disease; AIDS, Acquired immune deficiency syndrome; AQP3, Aquaporins 3; ARDS, Acute respiratory distress syndrome; CAT, COPD assessment test; CC50, 50% Cytotoxic concentration; CCL-2/MCP-1, CC motif ligand 2/monocyte chemoattractant protein-1; CFDA, China Food and Drug Administration; COPD, Chronic obstructive pulmonary disease; COVID-19; COVID-19, Coronavirus disease 2019; CPE, Cytopathic effect; CSS, Cytokine storm syndrome; CT, Computed tomography; CXCL-10/IP-10, C-X-C Motif Chemokine Ligand 10/ Interferon Gamma-induced Protein 10; Cytokine storm syndrome (CSS); DMSO, Dimethyl sulfoxide; E protein, Envelope protein; ERK, Extracellular signal-regulated kinase; FBS, Fatal bovine serum; Forsythia honeysuckle (Lianhuaqingwen,LH) capsules; Grb2, Growth factor receptor-bound protein 2; HIV, Human immunodeficiency virus; HPLC, High-performance liquid chromatography; HSV-1, Herpes simplex virus type 1; HVJ, Hemagglutinating virus of Japan; Hep-2, Human epithelial type 2; Huh-7, Human Hepatocellular Carcinoma-7; IAV, Influenza A virus; IBV, Influenza B virus; IC50, 50% Inhibition concentration; IFN-1, Interferon-1; IL-6, Interleukin-6; IL-6R, IL-6 Receptor; IL-8, Interleukin-8; IP-10, Interferon-inducible protein-10; JAK/STAT, Janus kinase/signal transducers and activators of transcription; JAK1/2, Janus kinase1/2; LD50, 50% Lethal dose; LH capsules, Forsythia honeysuckle (Lianhuaqingwen) capsules; M protein, Membrane protein; MAPK, Mitogen-activated protein kinase; MCP-1, Monocyte chemotactic protein 1; MDCK, Madin-darby canine kidney; MEK, Mitogen-activated protein kinase kinase; MERS, Middle east respiratory syndrome; MIP-1, Macrophage Inflammatory Protein-1; MLD50, 50% Minimum lethal dose; MOF, Multifunctional organ damage; MOI, Multiplicity of infection; MTT, Methyl Thiazolyl Tetrazolium; NF-kB, Nuclear transcription factor kappa-B; NHC, National Health Commission; ORFs, Open reading frames; PBS, Phosphate buffered saline; PHN, Phillyrin; PI3K, Phosphoinositide 3-kinases; PKA/p-CREB, Protein kinase A /phosphorylated cAMP response element-binding protein; PKB, Akt, Protein kinase B; PLpro, Papain-like proteases; PRC, People's Republic of China; QC, Quality control; RANTES, Regulated on activation normal T cell expressed and secreted; RSV, Respiratory syncytial virus; RT-PCR, Reverse transcription PCR; Ras, Ras GTPase; SARS-CoV-2; TCID50, 50% Tissue culture infective dose; TD0, Non-toxic Dose; TD50, Half-toxic dose; Vero E6, African Green Monkey Kidney Epithelial-6; gp-130, Glycoprotein 130; mIL-6R, Membrane-bound form IL-6 Receptor; mTOR, Mammalian target of rapamycin; nsps, Non-structural proteins; qPCR, Quantitative PCR.